Microscopic Features of Central Caseous Necrosis in Tuberculosis Lymphadenitis Patients: The Relationship with Lymphocyte Density

Tuberculosis lymphadenitis (TBLN) is the most common extra pulmonary TB (EPTB) case in world with a range of 30-40% all EPTB cases. When body's immune system cannot kill pathogen, body will try to contain pathogen (granuloma). The outer portion granuloma becomes calcified and cells center undergo necrosis. formation central necrosis associated emergence cellular hypersensitivity features local accumulation macrophages lymphocytes. current study aimed determine relationship between microscopic caseous lymphocyte density patients tuberculous lymphadenitis. Thirty histopathological slides TBLN were observed under microscope see assess results assessed based on cutoff point median mean values. Based examination, 25 samples found other 5 not have Twenty-six had low density, 4 high density. Fisher Exact test obtained p = 0.009. There significant TBLN.